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Depend Night Defense is an adult diaper in the Depend line made for overnight use. As of now there is only a women's version.


The Depend Night Defense comes in three sizes:

Size Waist Hips Weight
S/M 28-40 in 34-46 in 115-190 lbs
L 38-50 in 44-54 in 170-260 lbs
XL 48-64 in 48-64 in 200-300 lbs

Where To Buy

  • Most grocery stores, pharmacies, big box stores and their associated websites
  • Amazon